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Hoffenheim vs Lyon prediction: team news, lineups, expert analysis

The visitors will avoid defeat
Benjamin Mcneil
Author:
Benjamin Mcneil, betting expert
Published:
Hoffenheim vs Lyon match prediction on 22.10.26
Math prediction 1 X 2
2.07 Linebet 18 Oct 20:02 2.01 + 0.06 16 Oct 20:01 2.58 -0.57 3.98 Linebet 16 Oct 20:01 3.75 + 0.23 3.36 Linebet 18 Oct 20:02 3.55 -0.18 16 Oct 20:01 2.66 + 0.89
47% 24% 29%
33 TIPS
Tournament Europa League
Venue SNP Arena (Sinsheim)
Date & kick-off time

On October 22, 2026, Hoffenheim and Lyon will meet in the third round of the Europa League league phase. The visitors will try to pick up points away against their neighbors.

Hoffenheim vs Lyon: team news and expert analysis

The club from Sinsheim could have returned to the Bundesliga's top four, but settled for fifth place in the spring. Now, however, they have started losing too often right from the outset. Olympique had a stronger 2025/2026 campaign, finishing fourth in Ligue 1 in the spring. They have also made an unbeaten start this season, heading into the international break in second place—above PSG.

The Germans also suffered defeat in European competition. They were completely outplayed, losing 0-2 to OGC Nice. After the "FIFA window," they scored twice at home against Beşiktaş but conceded even more, eventually losing 2-3.

The French side began their campaign in the Champions League. After edging past Sparta Prague, albeit with some difficulty, they then lost to Fenerbahçe, suffering defeat at home after drawing in Istanbul. In the current tournament, they opened with an away win over Anderlecht. At home against Crystal Palace, they prevailed in a shootout, winning 3-2.

Previous matches: Hoffenheim vs Lyon

The clubs met in the Champions League in 2018 and crossed paths in the Europa League two seasons ago. Every encounter ended in a high-scoring draw.

The visitors are not widely fancied, but they look strong compared with their opponents. They should avoid defeat away from home (odds – 1.78).

Hoffenheim vs Lyon: key statistics and trends

  • Hoffenheim have lost both of their previous matches in the competition
  • Hoffenheim score an average of 1.83 goals and concede 2.33 goals per match
  • Both teams have scored in 100% of Hoffenheim's matches, while the average total is 4.17 goals per game
  • Lyon have won three of their six matches in European competition
  • Lyon score an average of 1.86 goals and concede 0.71 goals per match
  • Both teams have scored in 57% of Lyon's matches, while the average total is 2.57 goals per game

Hoffenheim vs Lyon: possible starting lineups

Hoffenheim play in a 1-4-2-3-1 formation (possible lineup): Baumann - Roths, Haidari, Kabak, Coufal - Burger, Avdullahu - Hlozek, De Ketelaere, Wimmer - Lemperle

Lyon play in a 1-4-3-3 formation (possible lineup): Descamps - Ouédraogo, Niakhaté, Mata, Kluivert - Nartey, Morton, Tessmann - Nakamura, Openda, Budash

Follow the Europa League standings and learn about your team's form before placing a bet on the next match

Our Pick
Game Prediction Lyon won't lose
1.78
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Benjamin Mcneil
Benjamin Mcneil
betting expert
He is an analyst in the world of football who doesn't mind adding to his budget with a lucky bet, something he has been doing for the last 10 years. I don't believe in luck, but I believe that the motivation of the opponents and their kit plays a big role, and any sensation is explainable. I prefer to play cautiously, because it is better to win 5 out of 5 bets at odds of 1.6-1.7 than to lose 2 out of 3 bets at odds of 2.2.
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Avr. Coef. Avr. Coef. for the last 30 days 1.73
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Game Prediction Our Pick
Lyon won't lose
1.78