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OFI vs Bayer prediction: expert analysis, possible lineups, October 22, 2026

The visitors can win by more than a narrow margin
Benjamin Mcneil
Author:
Benjamin Mcneil, betting expert
Published:
OFI Crete vs Bayer Leverkusen match prediction on 22.10.26
Math prediction 1 X 2
12.4 Linebet 18 Oct 20:01 11.9 + 0.5 17 Oct 20:01 10.6 + 1.3 16 Oct 20:00 8.6 + 2 6.74 Linebet 18 Oct 20:01 6.59 + 0.15 17 Oct 20:01 6.23 + 0.36 16 Oct 20:00 5.42 + 0.81 1.25 Linebet 16 Oct 20:00 1.37 -0.08
8% 14% 78%
29 TIPS
Tournament Europa League
Venue Pankritio Stadium
Date & kick-off time

The match between OFI and Bayer will take place on October 22, 2026, in the third round of the Europa League league phase. Few will understand if the visitors drop points here.

OFI vs Bayer team news and expert analysis

The club from Heraklion finished only seventh last season — but unexpectedly lifted the domestic cup. After a strong start to the current league campaign, they also claimed the Super Cup. Following Xabi Alonso's departure, the Leverkusen side finished only sixth in 2025/26. They have already suffered setbacks in the opening rounds this season as well.

The Greeks have pleasantly surprised with their start in European competition. In August, they defeated CSKA Sofia in both legs of the qualifying round. In the autumn, they secured a convincing 2-0 win over another German side, Hoffenheim. They also scored against Rennes, but this time lost 1-2.

The Germans comfortably dealt with Celje in the opening round, scoring a couple of unanswered goals against the modest visitors. Against Lech in October, they went one step further and recorded a commanding 4-0 victory.

Previous matches: OFI vs Bayer

This will be the clubs' first-ever meeting.

The visitors are in good form and have plenty of experience. We recommend backing them to win this match away from home with a -1.5-goal handicap (odds — 1.67).

OFI vs Bayer: key statistics and trends

  • OFI have won three of their four league matches
  • OFI score and concede an average of 1.57 goals per match
  • Both teams have scored in 43% of OFI matches, with an average total of 3.14 goals per game
  • Bayer have won their previous two matches
  • Bayer score an average of 2.67 goals and concede 1.5 goals per match
  • Both teams have scored in 67% of Bayer matches, with an average total of 4.17 goals per game

OFI vs Bayer: possible starting lineups

OFI play in a 1-3-4-3 formation (possible lineup): Christogeorgos — Krizmanic, Pungouras, Kotsoulas — Athanasiou, Bouchalakis, Androutsos, Dieckmann — Kantalapiedra, Kodro, Fountas

Bayer play in a 1-4-2-3-1 formation (possible lineup): Flekken — Medina, Tapsoba, Bade, Vazquez — Garcia, Andrich — Tillman, Diaby, Terrier — Schick

Place your bets on the upcoming match and follow your team's position in the Europa League standings

Our Pick
Game Prediction W2(-1,5)
1.67
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Benjamin Mcneil
Benjamin Mcneil
betting expert
He is an analyst in the world of football who doesn't mind adding to his budget with a lucky bet, something he has been doing for the last 10 years. I don't believe in luck, but I believe that the motivation of the opponents and their kit plays a big role, and any sensation is explainable. I prefer to play cautiously, because it is better to win 5 out of 5 bets at odds of 1.6-1.7 than to lose 2 out of 3 bets at odds of 2.2.
WinRate WinRate (%) for the last 30 days 56
Avr. Coef. Avr. Coef. for the last 30 days 1.73
Void Voided bets (postponements, cancellations, etc.) in the last 30 days 70
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Game Prediction Our Pick
W2(-1,5)
1.67