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Southampton vs Arsenal prediction: team news, lineups, expert analysis

The hosts could surprise here
Benjamin Mcneil
Author:
Benjamin Mcneil, betting expert
Published: 02 Apr 2026, 12:50
Southampton vs Arsenal match prediction on Apr 04, 2026
Math prediction 1 X 2
6.79 5.16 1.45
14% 19% 67%
37 TIPS
Tournament FA Cup England
Date & kick-off time 04 apr 2026, 15:00

In the FA Cup quarterfinal on April 4, 2026, Southampton will face Arsenal. The favorite is obvious, but the underdog may take advantage of the opponent’s potentially low motivation.

Southampton vs Arsenal: Team News and Expert Analysis

The club from "St. Mary’s" has become something of an "elevator" between divisions. They were in the Championship in 2023/2024, and after immediately returning to the Premier League, found themselves among the weakest. This season started poorly, but after appointing Tonda Eckert, the players started winning frequently and are clearly targeting a play-off spot. Before the break, they claimed another victory over Oxford.

The capital’s giants are having an excellent season. March ended with a League Cup final against Manchester City, which they lost 0-2. However, in the Premier League, they are leading the title race against the same team. In the Champions League, their only failure was away at Bayer Leverkusen, but they beat the Germans 2-0 at home in the return leg of the Round of 16.

The hosts have won three matches by a single goal margin. Against Doncaster, it was 3-2 away, then they managed a 2-1 home win over Leicester. Versus Fulham, they scored the only goal from the penalty spot in stoppage time. The London stars scored four times against both Portsmouth and Wigan, but only managed a 2-1 win over Mansfield.

Previous matches: Southampton vs Arsenal

Last season, both encounters were won by Arteta’s side.

The visitors are clear favorites, but the tournament is not a priority for them. Here, we recommend backing the hosts with a "+2.0 goals" handicap (odds – 1.60).

Southampton vs Arsenal: Key Statistics and Trends

  • Southampton have won twelve of their last sixteen matches
  • On average, Southampton score 1.62 goals and concede 1.23 goals per match
  • 69% of Southampton’s matches end with both teams scoring and the average total goals per match is 2.85
  • Arsenal have won six of their last eight games
  • On average, Arsenal score 1.97 goals and concede 0.71 goals per match
  • 48% of Arsenal’s matches end with both teams scoring and the average total goals per match is 2.68

Southampton vs Arsenal: Possible Starting Lineups

Southampton play in a 1-4-2-3-1 system (possible lineup): Perez – Manning, Wood-Gordon, Harwood-Bellis, Bree – Yander, Downes, Sienza, Azaz, Fellows – Larin

Arsenal play in a 1-3-5-1-1 system (possible lineup): Arrizabalaga – Calafiori, Mosquera, Salmon – Martinelli, Havertz, Trossard, Nørgaard, Douman, Madueke – Gabriel Jesus. Merino, Ødegaard, and Timber will not play.

Follow the FA Cup standings and track your team’s form before placing your next bet.

Our Pick
Game Prediction W1(+2)
1.6
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Benjamin Mcneil
Benjamin Mcneil
betting expert
He is an analyst in the world of football who doesn't mind adding to his budget with a lucky bet, something he has been doing for the last 10 years. I don't believe in luck, but I believe that the motivation of the opponents and their kit plays a big role, and any sensation is explainable. I prefer to play cautiously, because it is better to win 5 out of 5 bets at odds of 1.6-1.7 than to lose 2 out of 3 bets at odds of 2.2.
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Game Prediction Our Pick
W1(+2)
1.6